Ventrilia – Cardiovascular Tests

Description

WHAT IS Ventrilia ?

Ventrilia is a new generation genetic test that analyses 292 genes to detect mutations that cause multiple cardiovascular conditions with complex phenotypes.

By identifying genetic mutations that could cause cardiovascular diseases, Ventrilia can provide you with comprehensive genetic insight about your patient’s cardiovascular health and guide you towards an optimal clinical management plan

Ventrilia can be used to:

• Identify the genetic variant in symptomatic individuals with a clinically diagnosed cardiovascular condition
• Identify the genetic variant in pre-symptomatic individuals with a clinically diagnosed cardiovascular condition
• Identify the genetic variant in asymptomatic individuals that belong in high-risk groups

WHO IS Ventrilia FOR?

• Symptomatic patients with an unidentified cardiovascular genetic disorder
• Pre-symptomatic patients with family history of inherited cardiovascular disease or sudden cardiac death
• Patients experiencing fainting or unexplained seizures
• Patients experiencing fainting or unexplained seizures Patients with clinical diagnosis of aortic defect, or irregular cardiovascular anatomy
• Patients with clinical diagnosis of channelopathies (irregular heart rhythm)
• Patients suspected of having a cardiovascular-associated genetic condition due to clinical symptoms (shortness of breath, excessive sweating, heart pain, weakness)
• Patients in high-risk groups (eg. high cholesterol) with non-specific phenotype

 WHAT ARE THE BENEFITS OF Ventrilia?

• Faster identification of complex cardiovascular conditions
• Accurate detection of multiple cardiovascular genetic mutations
• Early identification in asymptomatic patients
• Improved prognosis
• More e­ffective treatment
• Better clinical care
• Prevention of potential sudden onset of cardiovascular conditions, including sudden death in all patients

Pain free sample collection with a Buccal Cheek Swab – can be carried out in the comfort of your own home

Results available within 21 – 28 working days of sample arriving in the laboratory

We always recommend that Test results are discussed with your Healthcare Professional

CARDIOVASCULAR DISEASE PANELS

Ventrilia tests for autosomal recessive, autosomal dominant, and X-linked cardiovascular diseases

 AORTOPATHY PANEL – (48 Genes) – £385

Aortopathy refers to a group of diseases that a­ect the aorta, causing enlargement, dissection or aortic aneurysm. Aortopathy related diseases include: Marfan Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, Familial Thoracic Aortic Aneurysms and Dissections, Bicuspid Aortic Valve Disease

ARRYTHMIA PANEL (42 Genes) – £385

Arrhythmia refers to irregular, too fast, or too slow heartbeat caused by the improper working of the electrical impulses that coordinate the heartbeat. Arrhythmia related diseases include: Atrial Fibrillation, Brugada Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia, Long QT Syndrome, Short QT Syndrome

CARDIOMYOPATHY PANEL (98 Genes) – £385

Cardiomyopathy is a group of diseases of the heart muscle (myocardium) which reduces the efficiency of the heart to pump blood. Cardiomyopathy related diseases include: Arrhythmogenic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy, Cardiomyopathy with onset in neonatal period, infancy or childhood, Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Left Ventricular Non-Compaction Cardiomyopathy, Restrictive Cardiomyopathy

CONGENITAL HEART DEFECTS PANEL (80 Genes) – £385

Congenital heart defects are present from birth and aff­ect the heart’s structure and efficiency to function. CHD related diseases include: Atrioventricular Septal defect, Atrial Septal defect, Ventricular Septal defect, Aortic Stenosis, Tetralogy of Fallot

FAMILIA HYPERCHOLESTEROL PANEL (11 Genes) – £385

Familial Hypercholesterolemia is a common inherited genetic disorder that causes high levels of LDL and could lead to heart disease and heart attacks, if untreated.

PULMONARY HYPERTENSION PANEL (11 Genes) – £385

Pulmonary Hypertension refers to the high blood pressure in the arteries of the lungs and the right side of the heart.

RASOPATHIES PANEL (30 Genes) – £385

RASopathies are a group of genetic conditions that a­ect the RAS-MAPK pathways and lead to developmental syndromes. RASopathies related diseases include: Cardio-Facio-Cutaneous Syndrome, Costello Syndrome, Legius Syndrome, Neurofibromatosis Type 1, Noonan Syndrome, Noonan with multiple lentigines

 COMPREHENSIVE PANEL (292 Genes) – £899

The comprehensive panel includes all 292 genes tested in the individual panels.

Please click here to view panel list 

Please click here to view gene list

Please click here to view brochure

We always recommend that Test results are discussed with your Healthcare Professional