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Price range: £755.00 through £1,215.00
The OncoNext Risk hereditary cancer risk test checks selected inherited gene changes linked to a higher chance of particular cancers. You can choose from 10 focused cancer-group panels or the broader Oncoscreening Complete option.
This range can help you explore whether inherited risk may contribute to a personal or family pattern of cancer. Through My DNA Lab, you can access the testing privately and use the report to support an informed conversation with your GP, a clinical genetics professional or a cancer genetics specialist.
A 10 ml blood sample is required. You can arrange collection with your own qualified healthcare professional or use My DNA Lab’s mobile phlebotomy service within mainland UK. Once your sample is ready, contact us and we will arrange its return to the laboratory.
Most cancers are not caused by an inherited gene change. However, some changes are present from birth and can increase the chance of particular cancers. Because an inherited change can be shared through a biological family, the result may also matter to relatives.
OncoNext Risk checks selected inherited changes in genes involved in functions such as DNA repair and control of cell growth. In other words, it assesses inherited predisposition; it does not analyse DNA released by a tumour or diagnose whether cancer is present now.
The exact genes differ between the focused cancer groups and the wider option. You can read about the current range in the OncoNext Risk brochure under ‘Test provider and further information’ further down this page.
OncoNext Risk may suit you if cancer has occurred at a younger age than expected in your personal or family history. It may also be relevant when several related cancers occur on one side of the family, or there is more than one primary cancer, a rare tumour or a known inherited cancer gene change.
If a genetic change has already been identified in your family, a focused test designed to look for that change may be more useful than a new broad panel. If you choose to use pre-test genetic counselling, you can decide whether to discuss the existing family report during that session.
If you have a new symptom or concern about cancer, speak with your GP. OncoNext Risk is designed to assess selected inherited risk and should not be used instead of symptom assessment, NHS screening or cancer follow-up.
My DNA Lab’s mobile phlebotomy service is available within mainland UK for an additional £60. Alternatively, you can arrange collection with your own qualified healthcare professional.
Your report may identify an inherited gene change linked to a higher chance of cancer, find no relevant change or identify a finding that needs further investigation. Each outcome has a different meaning and may lead to different follow-up questions.
A positive result does not mean that cancer is certain. Equally, a negative result does not remove ordinary cancer risk or rule out gene changes and cancer types outside your selected panel.
Free genetic counselling is available both before and after this test. Pre-test counselling can help you understand the panel choices, while post-test counselling can help explain what a finding may mean for screening discussions and biological relatives. To use either service, contact My DNA Lab and we will put you in touch with a representative from the testing provider. We always recommend that you discuss your results with your healthcare professional before making a major medical decision.
Whatever the result, continue routine NHS screening and seek medical advice for symptoms. Do not change screening or make a major medical decision from the report alone.
Begin with your personal and family history. Record which relatives had cancer, the cancer type, their age at diagnosis and which side of the family was affected. This can help you identify the cancer group that most closely matches the pattern you want to explore.
If several related cancer types occur on the same side of the family, or the pattern does not fit one focused option, the broader panel may be more relevant. However, wider testing can also increase the chance of an uncertain or unexpected finding.
A result may also matter to biological relatives. Consider whether you want to receive information with possible family implications and keep any questions with the report for your post-result discussion.
Keep the complete laboratory report with the family history. Relatives should not rely on a screenshot to decide that they have the same gene change, as they may need their own advice and focused testing.
